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The OxyR regulon includes genes encoding peroxiredoxins and catalases, as well as several other factors important for responding to oxidative damage, including the reducing agents glutathione reductase ( gor ), glutaredoxin 1 ( grxA) , and thioredoxin 2 ( trxC ), which function to minimize the frequency of aberrant disulfide bond formation occurring as a result of exposure to ROS (Zheng et al., 1998, 2001